Marlon King could start for Hull after joining on loan, while Caleb Folan has recovered from a muscle strain.
Peter Halmosi, George Boateng, Anthony Gardner, Bernard Mendy and Geovanni will be hoping to make their debuts.
Fulham will kick off the season without £10.5m striker Andrew Johnson, who is recovering from a thigh problem.
Diomansy Kamara (knee) is missing, but Mark Schwarzer, Fredrik Stoor, Zoltan Gera and Bobby Zamora are among those hoping to make their Fulham debuts. <!-- E SF -->
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Hull City (from): Myhill, Ricketts, Turner, Gardner, Dawson, Fagan, Ashbee, Boateng, Marney, Geovanni, Windass, Doyle, Hughes, Garcia, Cooper, Barmby, France, Halmosi, Featherstone, King, Mendy, Warner.
Fulham (from): Schwarzer, Zuberbuhler, Stockdale, Stoor, Pantsil, Volz, Hangeland, Hughes, Konchesky, Kallio, Andreasen, Bullard, Murphy, Davies, Gera, Andranik, Zamora, Nevland, Dempsey, Healy, Volz, Baird, Seol, E Johnson, Davis, Smertin.
Hull open a new chapter in their 104-year club history by playing in the top-flight of English league football for the first time.
In gaining promotion through the play-offs, the Tigers become the 42nd different club to play in the Premier League.
Fulham escaped relegation on the last day by goal difference last season, and begin an eighth successive campaign at this level.
The West Londoners ended last season on a role and could also make club history by recording four Premier League victories in a row for the first time.
Cottagers manager Roy Hodgson has been the busiest by far in the transfer market close season, shipping out 12 players and bringing in 10.